MS049 2HCl (1502816-23-0(free base)) ( —— )

产品货号. M19312 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

MS049 2HCl (1502816-23-0(free base))
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM).
产品描述

MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >130, >220, and 1.6 μM for PRMT1, PRMT3, and PRMT8, respectively) and displays no inhibition against type II or type III PRMTs nor any additional methyltransferases or nonepigenetic targets tested.
同义词

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通路

Others
靶点

Other Targets
受体

PRMT4; PRMT6
研究领域

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适应症

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1. Shen Y, etal. Journal of Medicinal Chemistry, 2016, 59(19):9124-9139.

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